lecture 15

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  • Created on: 21-05-14 11:04
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  • Lecture 15 - Pain
    • strongly unpleasant feeling caused by injury or illness
    • is adaptive and helps us to sruvive
    • Congenital analgesia?
      • unable to feel physical pain
    • Dolorimetry theory
      • All pain is same just varying inensity
    • Melzack (2005) theory
      • many different kinds of pain
    • biomedical characterisation?
      • Injury related action of specific receptors
    • biopsychosocial model (Edwards et al, 2009)
      • inter and intra individual diffs in coping with pain
    • Pain fibres
      • C
        • thin, unmyelinated, slow conductance
      • A delta
        • large diameter, myelinated, fast conductance
      • Signals to brain via spinothalamic system
        • spinal cord, medulla, pons, midbrain, thalamic nuclei, somatosensory cortex
    • Gate control theory (Melzack + Wall, 1965)
      • cognitive and emotional factors can block pain
      • descending signals activate neural circuits in spinal cords and block incoming signals
      • electrical stimulation of PAG
      • specialised receptors
      • endogenous opioids
    • descending pain inhib system
      • DLPFC + VLPFC
        • EXCITE
          • PAG
        • INHIB
          • Somatosensory cortices (SI, SII) and emotional regions (insula + thalamus)
    • Assessment
      • tolerance time
      • McGill pain scale
      • Wong-Baker faces
      • heart rate
    • Waccholtz and Pargament (2005)
      • meditation
    • Mitchell et al (2006)
      • music vs PASAT
    • Vincent et al (2010) nature images

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