Lateralisation

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  • Created by: meg_lou
  • Created on: 12-05-17 10:19
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  • Lateralisation
    • Lateralisation of function
      • Corpos Callosum
        • Separates left and right hemisphere
      • Marc Dax
        • Brain damaged patients with speech problems
          • Non had damage only in the RH
        • Language might be localised to one hemisphere of the brain
        • Brain was thought to act as a whole in the 1800's
      • Tests
        • Dichotic listening task
          • Most people report more of the digits presented to right ear
            • LH specialises in language
        • Sodium Amytal test
          • Injected into the neck which anesthetizes one hemisphere of the brain
            • Allows other hemisphere to be assessed
      • LH
        • Aphasia is a deficit in language due to brain damage in LH
          • Broca's - loss of speech but could comprehend e.g. Tan
            • Both aphasic patients had LH damage to prefrontal lobe
              • This became known as Broca's area, associated with speech production
          • Wernicke's - ability to speak but no comprehension
            • Patient suffered a stroke and was able to speak but could not understand what was said to him
              • Wernicke's area associated with speech comprehension
                • He suggested that broca's and wernicke's area are connected (arcuate fasciculus)
          • Language most lateralised of all abilities
        • Apraxia - bilateral difficulty performing movements when asked to do so
        • Analytical memory processing - relation of parts that make whole
      • RH
        • Able to understand single written/spoken words
          • Better at tasks for spatial ability, emotional stimuli and musical tasks
        • Holistic memory processing - parts or whole but not relation between
    • The split brain
      • Myers and Sperry
        • Four groups of cats: corpos callosum severed, optic chiasm severed, both severed, controls
        • Phase 1 - cats learned a level-press pattern discrimination task with a patch over one eye
        • Phase 2 - the patch was switched to the other eye
        • Group 3 acted if the task was new to them
        • Found that the corpos callosum transfers learned information between hemispheres
          • When cut, each hemisphere functions independently
      • Humans
        • First operations to sever corpos callosum performed on patients with severe epilepsy
          • Reduce severity of convulsions by restricting epileptic charges to half the brain
        • Tests of split brain patients
          • Visual stimuli flashed to right or left of fixation point on screen
            • Presented to LH - view/touch with right hand and name it
            • Presented to RH - view/touch with left hand but could not name it
              • LH involved with language!
          • Cross-cuing
            • Red or green light flashed to LVF
              • Patient improved gradually, suggesting that the colour information was being transferred over neural pathways
                • Not true - patient would  shake their head if they made a wrong guess
                  • RH heard incorrect guess and signalled it was wrong by shaking of the head
                    • Cued the LH to correct itself
        • Learning 2 things at once
          • Pencil in LVF and orange in RVF
            • Patient grasped both object and said there were 2 oranges
              • LH then saw it was a pencil and a orange
          • Helping hand phenomenon
            • Pencil in LVF and orange in RVF
              • Right hand reaches to pick the orange under direction of LH
                • Left hand would grab the right hand and direct it to the pencil
    • Cerebral asymmetry
      • Analytic-synthetic theory
        • Different modes of thinking, analytic (LH) and synthetic (RH)
          • LH - logical and analyses stimulus information
          • RH - makes overall judgements but cannot quantify it
        • Became segregated through evolution
          • Difficult to test empirically as  it is not possible to specify degree of analytic or synthetic processing
      • Motor theory
        • LH specialised for fine motor movement e.g. speech
        • LH lesions disrupt facial movements more than RH lesions
          • Degree of disruption of nonverbal face movements is positively correlated with degree of aphasia
          • Consistent with mirror neuron theory
        • Doesn't say why motor function became lateralised
      • Linguistic theory
        • Primary role of LH is language
          • Based on studies of deaf people using ASL with unilateral brain damage
            • WL had difficulty signing and understanding others signs
              • Was able to produce and understand other gestures - aphasia not a result of motor or sensory deficits
        • Other theories see it as a secondary function
  • Survival advantages of lateralisation
    • The 5 classes of vertebrates all have lateralised brains
    • Efficient to locate similar neurons next to each other
    • Two different kinds of tasks might be easier to perform
    • Language is highly specialised and unique to humans
      • Other primates also communicate by sounds with specific meanings

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