Krebs Cycle

HideShow resource information
  • Created by: Jelena
  • Created on: 23-03-13 21:24
View mindmap
  • Krebs Cycle
    • Location: mitochondrial matrix
    • Aerobic (doesn't directly use oxygen)
    • 8 steps
    • Oxaloacetate recycled
    • Final count: 8 NAHD, 2 FADH2, 2 ATP, 6CO2
    • The point is to make NADH and FADH
  • Preparatory Steps
    • Purpose : convert pyruvates to acetyl-CoA (2 carbon molecules)
    • Pyruvate enter mitochondria
    • Pyruvate is oxidized (1 carbon removed = decarboxylation) and H+ given to NAD+ --> becomes NADH
    • Coenzyme CoA attaches to pyruvate, creating acetyl CoA
    • CO2 molecules is released
  • Step 1
    • Acetyl CoA = 2 carbon atom
    • Acetyl CoA attaches to oxaloacetate (4 carbon sugar) to create citrate (6 carbon sugar)
  • Step 2
    • Citrate becomes isocitrate (6 carbon sugar)
  • Step 3
  • Step 4
    • ?-ketoglutarate loses H+ to NAD+ = NADH
    • CO2  is released
    • Coenzyme A molecule is added
    • Succinyl CoA (4 carbon sugar) is formed
  • Step 5
    • CoA binds to succinyl CoA
    • GTP is made
    • GTP donates phosphate group to ADP to make one ATP
    • Succinyl CoA becomes succinate (4 carbon sugar)
  • Step 6
    • Succinate sends 2 H+ to FAD = FADH2
    • Succinate is oxidized, FAD is reduced
    • Succinate becomes fumarate (4 carbon sugar)
  • Step 7
    • H2O added to fumarate = malate (malate)
  • Step 8
    • Malate reduces NAD+ to make NADH
    • This makes oxaloacetate
    • Oxaloacetate units with acetyl CoA to start the reaction again

Comments

No comments have yet been made

Similar All resources:

See all All resources »