Kidney Failure
- Created by: Sophie
- Created on: 27-04-13 13:02
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- Kidney Failure
- If kidney's don't work properly waste substances build up, lose ability to control levels of ions and water in the body.. eventual death
- Dialysis machines filter the blood
- Has to be done regularly to keep concentrations of dissolved substances in the blood at normal levels and to remove waste substances
- 3 times a week, 3-4 hours per session
- Blood flows alongside a partially permeable membrane and dialysis fluid. Large molecules e.g proteins cannot get past the membrane.
- Only waste substances and excess ions and water diffuse across the membrane
- The dialysis fluid contains the same concentration of dissolved ions and glucose as healthy blood
- Useful dissolved ions and glucose on't be lost from blood during dialysis
- May cause blood clots or infection
- DISADVANTAGES: Disrupts routine, risk of infection
- ADVANTAGES: No waiting list, immuno suppresants not needed
- Has to be done regularly to keep concentrations of dissolved substances in the blood at normal levels and to remove waste substances
- Transplants
- Only cure for kidney disease
- Donor kidney can be rejected from patient's immune system due to the foreign antigens, the patient's antibodies attack these
- SO a donor with a closely matching tissue type is chosen
- Drugs needed to suppress immune system- immuno suppresents so the kidney won't be rejected
- DISADVANTAGES: Long waiting lists for donors, immuno suppressants mean patient is vulnerable to illness
- ADVANTAGES: Cheaper in the long run, doesn't disrupt routine, high surgery risk
- Damage from an infection of disease, less than 30% activity
- e.g long term high blood pressure, kidney stones
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