Kidney

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  • Created by: KayshaN
  • Created on: 29-10-17 19:14
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  • Kidney
    • Structure
      • Three main areas:
        • the cortex- dark outer layer, filtering of blood takes palce
        • the medulla- lighter colour tubules of nephron, pyramids and collecting ducts
        • the pelvis- central chamber where urine collects
      • Nephron
        • Bowman's Capsule
          • cup shaped, contains glomerulus
            • Untitled
        • Proximal Convoluted Tubule
          • first coiled region of tubule. Substances reabsorbed
        • Loop Of Henle
          • long loop, descending limb and ascending limb
        • Distal Convoluted Tubule
          • second twisted tubule, water balancing of the body takes place
        • Collecting Duct
          • urine passes down through medulla to cortex, more water balancing
    • Function
      • Ultrafiltration
        • glomerulus supplied with blood wide afferent arteriole, out narrow efferent arteriole- pressure
          • blood out of capillary wall- sieve
            • passes through basement membrane except blood cells and proteins
              • wall of Bownman's capsule podocytes, additional filters. Extensions called pedicels wrap around capillaries- slits
                • if any big proteins get through basement, don't get into tubule
                  • Ultrafiltration
                    • glomerulus supplied with blood wide afferent arteriole, out narrow efferent arteriole- pressure
                      • blood out of capillary wall- sieve
                        • passes through basement membrane except blood cells and proteins
                          • wall of Bownman's capsule podocytes, additional filters. Extensions called pedicels wrap around capillaries- slits
                            • if any big proteins get through basement, don't get into tubule
        • Reabsorption
          • Proximal Convoluted Tubule
            • Loop Of Henle
              • Distal Convoluted Tubule
                • Collecting Duct
                  • Reabsorption
                    • Proximal Convoluted Tubule
                      • Loop Of Henle
                        • Distal Convoluted Tubule
                          • Collecting Duct
                            • balancing of water needs. If body lacks ions, actively pumped in. If water not needed, increase ADH, increase permeability.
                              • water diffuses out down collecting duct
                            • arrives isotonic to with blood and tissue fluid
                            • descending limb- water moves out down conc gradient, lower part permeable, ion conc moving through medulla increase due to AL
                            • not permeable to Na and Cl ions. Reaching hairpin very concentrated. Hypertonic to blood
                            • ascending limb- very permeable to Na and Cl. Out down conc gradient. Second section actively pumped out. Impermeable to water, cant follow
                            • fluid left, increasingly dilute. Top hyportonic to blood
                          • glucose, amino acids and hormones moved back in by active transport. Na moved by active transport, Cl ions and water move passively
                    • balancing of water needs. If body lacks ions, actively pumped in. If water not needed, increase ADH, increase permeability.
                      • water diffuses out down collecting duct
                    • arrives isotonic to with blood and tissue fluid
                    • descending limb- water moves out down conc gradient, lower part permeable, ion conc moving through medulla increase due to AL
                    • not permeable to Na and Cl ions. Reaching hairpin very concentrated. Hypertonic to blood
                    • ascending limb- very permeable to Na and Cl. Out down conc gradient. Second section actively pumped out. Impermeable to water, cant follow
                    • fluid left, increasingly dilute. Top hyportonic to blood
                  • glucose, amino acids and hormones moved back in by active transport. Na moved by active transport, Cl ions and water move passively

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