Cells and Organelles-Interaction of signal sequences with the ER membrane
- Created by: jessica
- Created on: 25-02-13 16:32
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- Interaction of signal sequences with the ER membrane
- Signal sequence on emerging polypeptide is exposed
- Signal recognition particle (SRP) binds to the signal peptide
- The SRP bound complex binds to the SRP receptor on the ER
- SRP and receptor dissociate and the signal peptide binds to the translocon and the gate opens
- The ribosome covers the gate and the protein loops into the translocon
- The polypeptide chain elongates through the translocon and the signal peptide is cleaved by signal peptidase
- The polypeptide chain enters the ER lumen and begins to fold
- Untitled
- The polypeptide chain enters the ER lumen and begins to fold
- The polypeptide chain elongates through the translocon and the signal peptide is cleaved by signal peptidase
- The ribosome covers the gate and the protein loops into the translocon
- SRP and receptor dissociate and the signal peptide binds to the translocon and the gate opens
- The SRP bound complex binds to the SRP receptor on the ER
- Signal recognition particle (SRP) binds to the signal peptide
- Signal sequence on emerging polypeptide is exposed
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