Infection

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  • Process of Infection
    • 1.Colonization
      • infectious microorganism exist in reservoir
        • transmitted by direct contact or by vectors
          • microorganism stable adherence to the tissues through specific surface receptors
    • 2.Invasion
      • infectious agent can invade surrounding tissues
        • developed mechanism to penetrate tissues and avoid host's non specific and specific defenses (inflammation and immunity)
    • 4. Spread
      • produce localized infections without spread to other regions of the body
        • others highly invasive - may enter lymphatics, blood, internal organs
          • successful spread - relies on virulence factors
            • intact immune system - microorganism remains localized
              • immune or inflammatory system  compromised  - infection may rapidly spread

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