Immunology
- Created by: Natalie Simon
- Created on: 17-12-14 20:59
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- Immunology
- Complement
- Classical: c1q/c1r/c1s/c4/c2
- C3b: Opsonisation
- MB Lectin: MBL/MASP/c4/c2
- C4a/c3a/c5a: Recruitment phagocytosis
- Alternative: c3/b/d
- c5b/6/7/8/9: Lysis
- Classical: c1q/c1r/c1s/c4/c2
- Gram Negative: LPS
- Gram Positive: Lipoteichoic Acid
- Collectins- Serum
- TLR1/2/6: Peptidoglycan, lipoproteins, lipoarabinomannan (mycobacteria), GPI (T cruzi), Zymosan (yeast)
- TLR 3: ds RNA
- TLR 5: Flagellin
- TLR 4: LPS Gram -
- TLR-9: Unmethylated CpG DNA
- NOD1: y-glutamyl diaminopimelic acid (GRAM - PGN) NOD 2: muramyl dipeptide
- Neutrophil: H2O2+Cl.=OCl. + H2O / OCl.+H2O=O2+Cl.+H2O/2O2-+2H+=H2O2+O2/H2O2= H2O + O2
- Macrophages: IFNy+TNFa= O2+ Arg= NO + Cit (NO synthetase/tetrahydrobiopterin)
- Untitled
- Complement
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