Immune system- 3 lines of defense

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  • Immune system- 3 lines of defence
    • Second line of defence
      • Non-specific
      • Comes into action if pathagon passes 1st line of defence
      • White blood cells
        • Phagocytosis
          • Phagocyte recognises antigens on pathagons
            • Cytoplasm of phagocyte moves around pathagon engulfing it!
              • Lysome fuses with phagocytic vacuole and enxymes break down the pathogen
                • Presents Antigen on surface
              • Pathagon contained phagocytic vacuole
    • First line of defence
      • Non-specific
      • Skin
        • Psychical barrier
        • Acidic PH kills microbes
      • Mucous membrances
        • Traps foreign pathagons
        • Lines respiratory tract entrances
      • Hairs and cilea
        • Traps foreign pathagons
        • Nose, ears,
      • Urine
        • Acidic fluid that has a protective element
      • Tears, sweat and saliva
        • Anti-bacterial properties
      • External layer
    • 3rd line of defence
      • Specific immune response
      • B-lymphocyte
        • Covered in antibodies
          • Bind to specific Antigen
            • Antigen-antibody complex
            • Antibodies join engulfing them
              • Killer-T-cells Kill the Pathagon.
      • T-Lymphocyte
        • Receptors on surface
          • Binds to specific antigen
            • Activates T-Lymphocytes
              • Divide to produce clones
                • Clonal activation
                • Helper-t-Cells
                  • Activate B-Lymphocytes
                    • B-lymphocyte
                      • Covered in antibodies
                        • Bind to specific Antigen
                          • Antigen-antibody complex
                          • Antibodies join engulfing them
                            • Killer-T-cells Kill the Pathagon.
                • Killer-T-Cells
                  • Kill the pathagon
                • Memory cells
                  • Remember the pathagon, to activate secondary response
              • Clonal selection

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