Specific Immune system - Lymphocytes

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  • Created by: emily.tx
  • Created on: 17-06-17 14:45
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  • Lymphocytes
    • T helper cells
      • Type of T lymphocyte
      • Produce interleukin's (type of cytokine)
        • Interleukin's produced then stimulate B cell activity
          • This then increases antibody production
            • stimulates production of other types of T cells
              • and stimulates macrophages to ingest pathogens with an:
                • Antigen-Antibody complex
      • Interleukin's produced then stimulate B cell activity
        • This then increases antibody production
          • stimulates production of other types of T cells
            • and stimulates macrophages to ingest pathogens with an:
              • Antigen-Antibody complex
    • T Killer Cells
      • Destroy the pathogen
      • Produce a chemical called Perforin:
        • This kills the pathogen by making holes in the cell membrane so its freely permeable
    • T memory Cells
      • Live for a long time
      • Part of the immunological response
      • If they meet an antigen for a second time, they divide rapidly to form T killer cell clones
    • T regulator cells
      • Surpress the immune system
      • Stop immune response once a pathogen has been eliminated
      • Checks the body recognises self antigens and doesn't set up autoimmune response
    • Plasma Cells
      • Produce antibodies to a particular antigen and release them into circulation
      • Active ones only live for a few days
      • Produce around 2000 antibodies per second when alive
    • B effector cells
      • divide to form plasma cell clones
    • B memory cells
      • Live for a very long time
      • Provide immunological memory
      • Programmed to remember a specific antigen
      • Produce rapid response when a pathogen carrying the antigen is encountered again
    • T Lymphocytes mature in Thymus gland
    • B lymphocytes mature in the bone marrow

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