Humoral and cell mediated immunity

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  • Created by: versailee
  • Created on: 03-03-20 16:24
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  • Immunity
    • Cell mediated immunity
      • 1- Pathogens invade body cells or are taken in by phagocytosis
        • 2-The phagocyte places antigens from the pathogen on its cell surface membrane
          • Receptors on certain T helper cells fit exactly onto these antigens
          • 3- This activates other T cells to divide rapidly by mitosis to form a genetically identical clone
            • The cloned T Cells either:
              • Develop into MEMORY CELLS
                • Enables a rapid response to future invasions by the same pathogen
              • Stimulate B Cells to divide, killing infected cells
              • Stimulate phagocytes to engulf pathogens by phagocytosis
    • Humoral immunity
      • B cells are covered in antibodies so they are specific to certain antigens.
      • 1. When a bacterium enters the bloodstream it will be ingested by a phagocyte
        • 2. T Helper Cells then attach to the antigens on the B Cells thereby activating them
          • 3. The B Cells are then activated to divide by mitosis to give a clone of the plasma cells
            • 4. The antibodies will then attach to the antigens on the pathogen and destroy them - Primary response
              • Some B Cells will develop into memory cells which respond to future infections by the same pathogen by dividing rapidly into plasma cells that produce antibodies - Secondary response
            • These cloned plasma cells produce antibodies that exactly fit the antigens on the pathogens surface
        • The phagocyte then presents the bacterium antigens on its cell surface
    • By Noor 12A.

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