Human Behaviour, Dopamine, and DNA
- Created by: jodie_lncstr
- Created on: 18-01-16 16:10
View mindmap
- Human Behaviour, Dopamine, and DNA
- Dopamine
- Low levels
- associated with Parkinsons Disease
- Parkinsons patients treated with L-dopa prone to behavioural changes (e.g compulsive gambling)
- Treatment involves clinical administration of dopamine precursor L-dopa
- Parkinsons patients treated with L-dopa prone to behavioural changes (e.g compulsive gambling)
- Treatment involves clinical administration of dopamine precursor L-dopa
- associated with Parkinsons Disease
- High levels
- associated with the development of mental health conditions e.g Schizophrenia
- increases general arousal
- decreases inhibition
- increase in creativity in conjunction with cerebral activity
- increases general arousal
- increase in creativity in conjunction with cerebral activity
- 5 different dopamine receptors
- named DRD1 through DRD5
- each coded for by a different gene
- 5 different dopamine receptors
- named DRD1 through DRD5
- each coded for by a different gene
- each coded for by a different gene
- named DRD1 through DRD5
- 5 different dopamine receptors
- each coded for by a different gene
- named DRD1 through DRD5
- Binding of dopamine to its receptor is involved in:
- control of motivation
- control of learning
- linked to regulatory effects on other neuro transmitter release
- number of antipsychotic drugs work by blocking dopamine receptors
- Low levels
- DRD4 Receptor Gene
- 50 known variants of DRD4 gene
- differ in specific sequence
- known as a variable number tandem repeat
- short section of nucleotides shows different no. of repeats in the variants
- variants are implicated in certain human behavioural conditions
- differ in specific sequence
- Inheritance of particular variants of the DRD4 gene affects the levels and action of dopamine in the braim
- ADHD
- Attention Deficit Hyperactivity Disorder
- drugs used to treat this (e.g Ritalin) effect dopamine levels in the brain
- a particular dopamine receptor variant of DRD4 is more frequent in those suffering from ADHD
- Particular variants of DRD4 receptor gene are implicated in increased likelihood of addictive behaviours
- including smoking and gambling
- L-dopa administered to one group, haloperiodal given to others
- haloperidol blocks dopamine receptors
- difference in general arousal
- significant difference in risk taking levels
- 50 known variants of DRD4 gene
- Other neuro transmitter influenced conditions
- OCD thought to be result of deficiency in serotonin
- OCD = obsessive compulsive disorder
- genetic wide scan for DNA sequences linked to OCD carried out
- 8 genetic markers found
- OCD thought to be result of deficiency in serotonin
- Dopamine
- Dopamine is a neuro-transmitter and hormone
- precursor molecule in the production of adrenaline and noradrenaline
- Dopamine
- Low levels
- associated with Parkinsons Disease
- Parkinsons patients treated with L-dopa prone to behavioural changes (e.g compulsive gambling)
- Parkinsons patients treated with L-dopa prone to behavioural changes (e.g compulsive gambling)
- associated with Parkinsons Disease
- High levels
- associated with the development of mental health conditions e.g Schizophrenia
- decreases inhibition
- increase in creativity in conjunction with cerebral activity
- increase in creativity in conjunction with cerebral activity
- Binding of dopamine to its receptor is involved in:
- control of motivation
- control of learning
- linked to regulatory effects on other neuro transmitter release
- number of antipsychotic drugs work by blocking dopamine receptors
- Low levels
Similar Biology resources:
Teacher recommended
Comments
No comments have yet been made