The control of blood glucose 2

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  • Created by: rahza
  • Created on: 19-08-17 16:28
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  • Insulin
    • signalling molecule
    • protein
      • cannot pass through cell membrane to stimulate the mechanism within the cell
    • insulin binds to a receptor in the cell surface membrane
      • cannot pass through cell membrane to stimulate the mechanism within the cell
      • And affects the cell indirectly through the mediation of intracellular messenger
        • insulin receptors are on many cells for eg: on liver cells
          • Insulin stimulates cells with these receptors to increase the rate at which they absorb glucose from the blood, convert it in to glycogen and use it in respiration.
            • This results in a decrease in the concentration of glucose in the blood.
    • stimulates the activation of the enzyme glucokinase, which phosphorylates glucose
      • This traps glucose inside cells, because phosphorylated glucosecannot pass through the transporters in the cell surface membrane
    • stimulates the activation of two other enzymes, phosphofructokinase and glycogensynthase, which together add glucose molecules to glycogen. This increases the size of the glycogen granules inside the cell

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