HIV
- Created by: tumblrgirl96
- Created on: 10-05-15 16:10
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- HIV
- Retrovirus
- Nucleic Acid = RNA
- Invades T helper cells
- gp120 molecules on virus surfaces bind to CD4 receptors on the surface of T helper cells
- Viral envelope then fused with the host cell membrane
- Viral RNA enters the cell
- Once inside the cell, viral DNA is manufactured from viral RNA using reverse transcriptase
- Viral DNA is integrated into host DNA using integrase
- It can then be transcribed and translated to produce new viral proteins
- Viral DNA is integrated into host DNA using integrase
- Once inside the cell, viral DNA is manufactured from viral RNA using reverse transcriptase
- Viral RNA enters the cell
- Viral envelope then fused with the host cell membrane
- new viruses bud out of T cell and take some of the host cell surface membrane with them as their envelope so they can't be destroyed
- Cell killed as they leave
- It can then be transcribed and translated to produce new viral proteins
- Destroyed by T killer cells.
- As number of viral cells increases, number of T helper cells decreases
- Macrophages, B cells and T killer cells not activated
- Don't function properly
- Leads to immune defficiency
- Macrophages, B cells and T killer cells not activated
- Don't function properly
- Leads to immune defficiency
- Leads to immune defficiency
- Don't function properly
- Macrophages, B cells and T killer cells not activated
- Leads to immune defficiency
- Don't function properly
- Macrophages, B cells and T killer cells not activated
- As number of viral cells increases, number of T helper cells decreases
- gp120 molecules on virus surfaces bind to CD4 receptors on the surface of T helper cells
- leads to AIDS
- Onset of AIDS
- Acute Phase
- Person experiences symptoms
- Fever
- Sweats
- Headache
- Rapid replication of virus and loss of T helper cells
- Reduced by infected cells being recognised
- Person experiences symptoms
- Chronic Phase
- No symptoms
- Other diseases can reactivate
- Disease Phase
- Onset of AIDS
- Decrease in number of T helper cells leaves immune system vulnerable
- high risk of infection by opportunistic infections
- Can lead to death
- Retrovirus
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