Glycolysis and the Krebs Cycle

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  • Glucose 6C outside cell
    • Glucose (6C)
      • Glucose Phosphate (6C)
        • Glycogen
        • Pentose and nucleotides
        • 2X Triose phosphate (3C)
          • ATP
          • Glycerol (3C)
            • Trigylcerides
          • Pyruvate (3C) Cytoplasm
            • Pyruvate (3C) inner mitochondrial membrane
              • Acetyl CoA (2C)
                • Fatty acids , inner mitochondrial membrane
                  • Fatty acids, cytoplasm
                    • Trigylcerides
                • Citrate
                  • CO2
                  • 5C
                    • CO2
                      • As before CO2 diffuses out of the cell
                • The acetyl CoA the enters the Krebs Cycle
                  • The 2C acetyl is transferred from acetyl coA to the 4C oxaloacetate, producing CO2 and H in the process
              • Once pyruvate has entered the inside of the mitochondria (matrix), it is converted to a compound called acetyl coA
                • Since this step links glycolysis and the Krebs cycle, it is referred to as the link reaction
                  • Pyruvate loses a CO2 and a H to form a 2C acetyl compound, which is temporarily attached to a mother coenzyme (coA)
              • CO2
                • Diffuses through the mitochondrial and cell membranes by lipid diffusion
              • H
                • Taken up by NAD
          • The triose sugar is changed over several steps to form pyruvate, a 3-carbon compound
          • 2ATP
          • H

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