Genes & Body Plans F215

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  • Created by: Shannagh
  • Created on: 03-02-15 19:38
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  • Genes & Body Plans
    • Mutations
      • Antennapedia - Legs appearing instead of Antenna
      • Mutagens
        • Retinoic Acid activates homeobx genes in vertebrates in the same order they are expressed.
          • If too much consumed by pregnant women the expression can be distorted. Can cause birth defects
          • Morphogen - governs the pattern of tissue development
    • Homeobox Genes
      • Maternal-Effect Genes determine embryos polarity
      • Segmentation Genes specify polarity of each segment
      • Contains sequence of 180 base pairs called the homeobox.
        • Produces 60 amino acids- some are transcription factors and regulate the expression of other genes
      • Arranged in Hox clusters
        • Nematodes have 1
        • Drosphilia have 2
        • Vertebrates have 4
      • Homeotic Selector Genes specify identy of each segment and direct development of individual body segments
        • Mutations
          • Antennapedia - Legs appearing instead of Antenna
          • Mutagens
            • Retinoic Acid activates homeobx genes in vertebrates in the same order they are expressed.
              • If too much consumed by pregnant women the expression can be distorted. Can cause birth defects
              • Morphogen - governs the pattern of tissue development
    • Genes control the development of the body plan including polarity and positioning of organs
      • Signal molecules activate homeobox genes after fertilization
      • Homeobox Genes
        • Maternal-Effect Genes determine embryos polarity
        • Segmentation Genes specify polarity of each segment
        • Contains sequence of 180 base pairs called the homeobox.
          • Produces 60 amino acids- some are transcription factors and regulate the expression of other genes
        • Arranged in Hox clusters
          • Nematodes have 1
          • Drosphilia have 2
          • Vertebrates have 4
        • Homeotic Selector Genes specify identy of each segment and direct development of individual body segments

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