Functions of the Liver
- Created by: tanya1
- Created on: 04-06-16 12:53
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- Functions of the Liver
- Synthesis
- Plasma Proteins
- Albumin
- Fibrinogen
- Prothrombin
- Bile
- Emulsifies fat
- Neutralises stomach acid
- Cholestrol
- Erythrocytes (foetus)
- Made in the bone marrow after birth
- Plasma Proteins
- Control
- Blood Glucose
- Lipids
- Concentrations
- Amounts
- Amino Acids
- Transamination- changes the R group.One amino acid is changed to another
- Excess AA's need to be excreted
- Deamination
- AA +O2 ----> Keto Acid +Ammonia
- Ornithine Cycle
- Storage
- Glycogen
- Iron
- Vitamins
- D
- A
- B12
- Breakdown
- Erythrocytes
- By Kupffer cells in sinusoids
- Produces Billirubin (brown pigment)
- Excreted in bile &faeces
- Produces Billirubin (brown pigment)
- Hormones
- Testosterone
- Oestrogen
- Removes Insulin
- Thyroxine
- By Kupffer cells in sinusoids
- Erythrocytes
- Detoxification
- Hydrogen Peroxide
- Converts Hydrogen peroxide to water and oxygen
- H2O2------>H2O+ 1/2 O2
- Liver contains catalase
- Drugs
- Barbiturates
- Antibiotics
- Paracetomol
- Can be: Oxidised , Reduced , Methylated or combined with another molecule
- Alcohol (Ethanol)
- Ethanal
- Ethanoic Acid
- Acetyl Co A
- Krebs Cycle
- Acetyl Co A
- NAD ----> Reduced NAD
- NAD is no longer used for oxidising fatty acids
- Fat deposits in the liver
- Scarring
- Cirrhosis
- Scarring
- Fat deposits in the liver
- NAD is no longer used for oxidising fatty acids
- Ethanoic Acid
- NAD ----> Reduced NAD
- Ethanal
- Hydrogen Peroxide
- Synthesis
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