Functional Recovery After Trauma & Technologies

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  • a form of plasticity following damaged through trauma, the brains ability to redistribute or transfer functions performed by a damaged area to other undamaged areas
    • Functional Recovery After Trauma
  • case studies of individuals suffering from strokes have found some individuals were able to recover previous functioning to some degree
    • The found the brain was able to 're-wire' itself and create alternative neural pathways around damaged areas
      • Able to do this through two mechanisms: neuronal masking and stem cells
        • Neuronal masking - axon sporuting as new nerve endings grown and connoect to undamaged areas
          • Reforming of blood vessels
          • Stem cell - unspecialised cells which have the potential to develop into various types of cells with different functions .
            • Treatment involving stem cells to inject them into the brain to replace dead or dying cells.
              • Can hellp the regeneration of damaged cells through secreting growth factors.
                • Evidence for stem cells aiding recovery - TARIJI ET AL - used rats with brain iinjuries while the other were a control group. Only the injured rats received stem cell implants into the areas of the injured brain and after 3 months they showed clear development of neuron-like cells on the injury sites
                  • Control group the opposite.
                    • Extrapolation - rats have different biology than human and the findings may lack external validity when generalizing to humans
  • Stem cell - unspecialised cells which have the potential to develop into various types of cells with different functions .
    • Treatment involving stem cells to inject them into the brain to replace dead or dying cells.
      • Can hellp the regeneration of damaged cells through secreting growth factors.
        • Evidence for stem cells aiding recovery - TARIJI ET AL - used rats with brain iinjuries while the other were a control group. Only the injured rats received stem cell implants into the areas of the injured brain and after 3 months they showed clear development of neuron-like cells on the injury sites
          • Control group the opposite.
            • Extrapolation - rats have different biology than human and the findings may lack external validity when generalizing to humans
  • Functional Magnetic Resonance Imaging
    • Measures changes to particular areas of the brain while individuals engage in various tasks
      • FMRI is non-invasive - not exposing brain to harmful radiation
      • Very expensive compared to other neuron technology machines
  • Electroencephalogram
    • Measures the general state of the brain. By measuring electrical activity in the brain through electrodes placed on the head which detects electrical activity of the brain cells.
      • Useful in clinical diagnosis, e.g. recording the abnormal neural activity associated with epilepsy.
        • Not useful for pinpointing the exact source of an acitivty
  • Event-related potential
  • Able to measure processing of stimulus
    • Time- consuming
    • Uses electrodes to measure very small voltage changes within the brain.
  • Post-mortem examination
    • Helps establish the underlying neurobiology for people that display particular sets of behaviour.
      • Played an essential role in understanding of schizophrenia
        • Hard to give informed consent if someone is dead

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