Eukaryotic RNA polymerases

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  • Created by: Ellie0o0o
  • Created on: 27-04-15 15:18
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  • Eukaryotic RNA Polymerases
    • 4
      • Nuclear x3
        • RNA Polymerase 1
          • Most rRNA
            • (The ribosome is number 1)
        • RNA Polymerase 2
          • mRNA, most sRNA, miRNA
            • Transcription and gene regulation
        • RNA Polymerase 3
          • tRNA, 5SRNA
            • Translation, the final step
            • 5S RNA is ribosomal
      • Mitochondrial x1
      • All different in structure
    • Discovered by labeling with radioactive UMP and fractionating cell
    • Has additional subunits to prokaryotes
      • Core subunits
        • Show homology to prokaryote polymerases
      • Common subunits
        • Additional units shared by all 3 eukaryote RNA Pols
      • Specific subunits
        • Specific to a particular polymerase
    • More stable than prokaryotic polymerases due to processing

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