Enzyme Inhibition

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  • Enzyme Inhibition
    • Inhibitors
      • Non - reversible
        • Slows down or stops an enzyme reaction
      • Reversible
        • Non - competitive
          • Bind away from the active site
          • Change the structure of the active site
            • The enzyme - substrate complex cannot form
        • Competitive
          • Compete with substrate for active site
          • Shape similar to the substrate
            • Allows inhibitor to enter active site
          • The more inhibitor, the slower the reaction
            • The active site is blocked more often
          • If the substrates cannot bond, less enzyme - substrate complexes will form
        • The majority of inhibitors are reversible

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