MONOCLONAL ANTIBODIES
- Created by: xxabbeymayxx
- Created on: 05-02-17 22:44
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- ELISA test
- uses of monoclonal antibodies
- pregnancy tests/diagnosis
- contain monoclonal antibody that specifically binds to hormone hCG
- hCG - secreted in early stages of preganancy
- sml quantity present in womens urine
- = monoclonal antibody attached to dipstick, any hCG in urine will bind too
- cause colour change
- = monoclonal antibody attached to dipstick, any hCG in urine will bind too
- contain monoclonal antibody that specifically binds to hormone hCG
- treat rheumatoid arthritis and crohns disease
- rheumatoid- caused when immune system fails to recognise some cells in joints as 'self'
- attacks them
- Crohns- results form immune system attacking lining of alimentary canal
- autoimmune diseases
- rheumatoid- caused when immune system fails to recognise some cells in joints as 'self'
- attacks them
- substance called TNF-alpha involved in this response
- if TNF-alpha disabled - immune system = calm down symptoms reduced
- Monoclonal antibodies developed that specifically bind to TNF-alpha and put it out of action
- if TNF-alpha disabled - immune system = calm down symptoms reduced
- rheumatoid- caused when immune system fails to recognise some cells in joints as 'self'
- autoimmune diseases
- rheumatoid- caused when immune system fails to recognise some cells in joints as 'self'
- used to kill cancer cells
- monoclonal antibodies - can be attached to drug that can kill cancer cells
- Monoclonal antibodies - produced that have complementary shapes to abnormal proteins (act as antigen) on particular cells
- combination molecules are then injected
- monoclonal antibody will bind to cancer cell and deliver srug at the same time
- avoiding harm to healthy cells which don't have same receptor
- monoclonal antibody will bind to cancer cell and deliver srug at the same time
- monoclonal antibodies - can be attached to drug that can kill cancer cells
- pregnancy tests/diagnosis
- Monoclonal antibodies - produced that have complementary shapes to abnormal proteins (act as antigen) on particular cells
- uses of monoclonal antibodies
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