Development and Discovery of Drugs.

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  • Discovery and Development of Drugs (4.3.1.9)
    • Describe how: most new drugs are synthesised by chemists in the pharmaceutical industry, but that the starting point may still be a chemical extracted from a plant.
    • Describe how: traditionally drugs were extracted from plants and microorganisms for example:
    • If the drug is found to be safe after initial trials, further clinical trials are carried out to find the optimum dose for the drug.
    • Describe how: preclinical testing is done in a laboratory using cells, tissues and live animals.
    • New drugs have to be extensively tested for toxicity, efficacy, and dose
    • In double blind trials, some patients are given a placebo.

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