Cholera
- Created by: Jessica
- Created on: 13-12-12 23:20
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- Cholera
- "Vibrio cholerae"
- Prokaryotic cell
- No true nucleus: - has a large circle of DNA
- No membrane bound organelles
- Smaller ribosomes (70s type)
- Cell wall made of polypeptides and polysaccharides
- Cytoplasm - Jelly like containing enzymes and other soluble materials
- Capsule covered in a mucilaginous layer of slime.
- Prokaryotic cell
- How it causes disease
- Most of the bacteria is killed by the acidic conditions of the stomach but a few many survive f the pH is above 4.5
- Use their flagellum to propel themselves through the intestinal wall
- Produce a toxin protein which has 2 parts to it
- The other enters the epithelial cells
- causes ion channels to open causing the chloride ions to flood into the lumen of the S.Intestine
- Raises W.potential in epithelial cells but lowers W.potential in the lumen
- this causes water to flow from the cells to the lumen
- One binds to the receptors of the cell surface membrane
- The other enters the epithelial cells
- Transmission
- water not properly purified
- untreated sewage leaks
- food contaminated by people who prepare and serve it
- organisms *such as shellfish) which have fed on untreated sewage released into rivers or sea
- "Vibrio cholerae"
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