cholera

mindmap of the process of how cholera works and its different stages. Explains in term of waterpotential aswell partly to highlight how it causes diarrhoea and dehydration. sources and solution also shown.

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  • Created by: mariam
  • Created on: 17-11-12 17:38
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  • Cholera
    • source
      • contaminated food and water
    • takes 1-5 ays for cholera to multiply in the small intestine and cause inflammation of it
      • starts to produce 2 tpres of toxin proteins
        • one types binds to carbohydrate receptors on the cell surface membrane- this explains why cholera toxin only affects this region of the body
        • 2nd type of toin--cholera binds to intestinal epethelial cells reeasing their toxins which bind to glycoprotein sugar groups projecting from epethelial cells.
          • cholera toxin activates an epethelial enzyme wich makes ATP convert to AMP
            • Increase of AMP stops Na transport from lumen into the blood
    • dehydration
      • Nacl in the lumen trys to mantain the osmotic balance so cells release water
    • how to get better
      • ORT(Oral Rehydration Therapy)
        • contains vital nutrients and ingredients
          • sodium, potassium,glucose
  • Higher water potential in epethelial cells than the lumen causes water to move out of the cells by osmosis causing water to flood the small intestine. This causes (watery faeces) diarrhoea.
    • Increase of AMP stops Na transport from lumen into the blood
  • how to get better
    • ORT(Oral Rehydration Therapy)
      • contains vital nutrients and ingredients
        • sodium, potassium,glucose

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