Cell and Molecular Biology

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  • Created by: jessica
  • Created on: 13-12-12 17:58
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  • Cell and Molecular Biology
    • Membrane Structure and function
      • phospholipid bilayer with lateral movement
      • unsaturated hydrocarbon tails enhance membrane fluidity
        • cholesterol reduces membrane fluidity
      • integral proteins penetrate hydrophobic core of lipid bilayer
      • peripheral proteins loosely bound to membrane surface
    • Actin filaments
      • polymerizes ATP/ADP
      • monomer is globular
      • Made of 2 strands bound in helix with 37nm repeat distance
      • 3 Types of actin network-cortical (gel like), stress fibres (contractile), tight bundle (stiffening)
    • Eukaryotic
      • DNA in nucleus
      • Contains ER, ribosomes, Golgi apparatus, Lysosomes, Mitochondrion, Peroxisome, Microvilli, Microfilament
    • Mitochondria
      • Has inner and outer membrane
        • Inner membrane has many folds called cristae
        • Matrix enzymes for citric acid cycle present
        • Outer membrane has porins
          • Porins are transport molecules
    • OILRIG
    • Intermediate filaments
      • tough durable protein polymers
      • found in nuclear lamina of muscle, epithelial cells and neurons
      • support cells and links to adjacent cells
    • Cell cycle
      • mitosis results in genetically identical daughter cells
      • meiosis develops haploid cells in gametes
      • Cytokinesis is the splitting of the cell into 2 by the formation of a cleavage furrow
    • Prokaryotic
      • bounded by plasma membrane, cytosol contains organelles
        • Eukaryotic
          • DNA in nucleus
          • Contains ER, ribosomes, Golgi apparatus, Lysosomes, Mitochondrion, Peroxisome, Microvilli, Microfilament
      • DNA in nucleoid
      • No membrane bound structures absent
    • Microtubules
      • 13 protofilaments
      • Polymerisation of microtubules
        • Untitled
      • Globular tubulin molecules

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