Signalling Pathway

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  • Created by: mina_l
  • Created on: 03-11-16 16:36
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  • Signalling pathway
    • gap junctions
      • Ions
      • Metabolites
        • sugars
        • ATP
        • cAMP
    • contact dependent(by membrane bound signal molecule)
    • autocrine
      • self-signalling
    • paracrine (by mediator molecule)
    • synaptic
    • endocrine( through bloodstream into the target cell)
    • Extracellular signal
      • chemical (e.g.: testosterone, insulin, acetylcholine)
        • ion channel linked receptors (undergo conformational change)
          • electrical signal
      • Role: transfer of information
      • combined
        • maintaining existance
        • differentiate
        • division
          • death
    • reception
      • transduction
        • amplification: second messengers
          • Cellular response
      • Extracellular signal
        • chemical (e.g.: testosterone, insulin, acetylcholine)
          • ion channel linked receptors (undergo conformational change)
            • electrical signal
        • Role: transfer of information
        • combined
          • maintaining existance
          • differentiate
          • division
            • death
      • inside the cell
        • steroid hormones
          • conformational change
            • regulates gene transcription
        • NO gas
      • cell membrane
        • cytokinases
        • neurotransmitters
    • physical (e.g.: light, pressure)
      • no receptor => no response

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