Core Concepts; Cell Membranes and Transport

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  • Cell Membranes & Transport
    • Membrane Structure
      • Phospholipids
        • form bilayers, hydrophiliic heads out & hydrophobic tails in
        • allow lipo-soluble molecules across
      • Proteins
        • extrinsic; on surface of membrane, provide support & form receptor sites
        • intrinsic: across the mebrane as transport protiens; carrier or channel
      • Cholesterol
        • makes more rigid & stable
      • Gylcoproteins/lipids
        • hormone receptors, cell to cell recognition
      • Fluid Mosaic
        • Fluid= proteins & phospholipids can move
        • Mosaic = proteins vary in size & shape
    • Transport
      • Facilitated Diffusion
        • ions & charged particles through transport proteins
        • passive as down gradient
      • Diffusion
        • passive as down gradient
        • affected by gradient, travel distance, surface area
      • Active transport
        • active as moves up gradient so requires energy
        • molecule enters carrier protein, phosphate group of ATP changes protein shape so molecule moves across & exits protein
      • Co-transport
        • brings molecules & ions in on same protein
        • e.g. sodium & glucose
      • Bulk transport
        • Endocytosis
          • material entering cell as engulfed by plasma & cytoplasm extension
          • phagocytosis: large solid fuse with lysosomes which digest molecuke
          • Pinocytosis: uptake of liquid
    • Osmosis
      • movement of water down conc gradient through partially permeable membrane
      • Water Potential
        • measure of water's free energy & tendency to move
        • the more negative the WP, the more likely water will move there
        • solutes decrease WP
      • Solute Potential
        • measures how easily water molecules move out of solution
      • Plant Cells
        • have pressure potential which is pressure when water enters & pushes cytoplasm against wall
        • hypOtonic solution
          • WP higher outside than in so water flows in cell
          • cell becomes turgid
        • hypERtonic solution
          • WP lower outside than in so water flows out
          • cytoplasm pulls away from wall (plasmolysis), cell is flaccid
        • Isotonic solution
          • Wp is equal so no net movement
      • Animal Cells
        • don't have cell walls so no pressure potential
        • water enters but cell bursts if too full, haemolysis
        • becomes crenated when water leaves

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