Carriage of Carbon Dioxide
- Created by: Eleanor Izzard
- Created on: 30-12-12 14:15
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- Carriage of Carbon dioxide
- In red blood cells
- CO2 released from repiring tissues
- diffuses into red blood cells
- combines with water under the presence of the enzyme carbonic anhydrase to from carbonic acid
- acid dissociates into hydrogen ions and hydro-carbonate ions
- hydro-carbonate ions diffuse out of the blood cell into plasma
- Chloride Shift - charge inside the RBC is maintained by Cl- ions moving into them
- H+ is taken up be haemoglobin to form haemoglobic acid - acting as a buffer
- oxy-haemoglobin dissociates under influence of hydrogen ions, releasing oxygen into the blood plasma
- hydro-carbonate ions diffuse out of the blood cell into plasma
- acid dissociates into hydrogen ions and hydro-carbonate ions
- combines with water under the presence of the enzyme carbonic anhydrase to from carbonic acid
- diffuses into red blood cells
- CO2 released from repiring tissues
- Bohr Effect
- when CO2 is present in RBC's, it displaces the oxygen in oxy-haemoglobin
- so more oxygen is released to the tissues
- where tissues are respiring more, more CO2 will be present
- so more H+ will be produced in RBC's, so more oxygen will be released
- when more C02 is present, haemoglobin is less saturated with oxygen, making the dissociation curve shift downwards and to the right
- so more H+ will be produced in RBC's, so more oxygen will be released
- when CO2 is present in RBC's, it displaces the oxygen in oxy-haemoglobin
- Transportation
- 10% combines with haemoglobin to from carbamino-haemoglobin
- 5% dissolved directly into blood plasma
- 85% in the from of hydrogen carbonates ions
- this is in the plasma
- In red blood cells
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