Cardiac disease in childbearing

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  • Created by: ljp101
  • Created on: 20-02-20 14:54
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  • Cardiac Disease in Pregnancy
    • Normal cardiovascular changes in pregnancy
      • Initial drop in BP in first trimester, then rise in BP from 34wks onwards
      • Increase in blood volume
      • Rise in pulmonary blood flow
      • Hormones relaxin and progesterone reduce venous wall resistance
      • Myocardial hypertrophy and chamber enlargement occur
      • Mild multivalvular regurgitation occurs
      • During labour cardiac output increases by 10-40% above pre-labour levels
      • Rapid intravascular volume shifts in 1st 2wks postpartum
      • Effects of these changes
        • Haemodilution - drop in Hb
        • Increased tiredness/ breathlessness on excretion
        • Ankle oedema
        • Varicose veins/ haemorrhoids
        • Jugular veins distend, obvious pulsation
        • Higher position of diaphragm, heart position moved
        • Heart enlarges
    • Effects of Cardiac disease (increased risk of...)
      • Mother
        • Miscarriage
        • Pre-term labour
        • C/S
        • Worsening of some cardiac conditions
        • Morbidity/ Mortality
      • Fetus/baby
        • Fetal death
        • Pre-term labour
        • IUGR
        • Neonatal morbidity/ mortality
        • Admission to NICU (side effects of maternal medication e.g. bradycardia, hypoglycaemia)
        • Inheritance of certain cardiac conditions
        • Requiring formula feeding (effects of some maternal drugs)
    • Incidence/ MBBRACE 2017
      • 2013-2015 8.8 women per 100,000 died during pregnancy or the puerperium
        • Two thirds of those women had pre-existing health problems.
      • Cardiac disease is the greatest cause of indirect deaths
      • Most deaths occurred in the postnatal period
      • Rate has remained fairly constant in recent years
      • Women with known heart disease are therefore high risk throughout
      • Cardiac disease remains the leading cause of indirect maternal death during or up to six weeks after the end of pregnancy with a rate of 2.34 per 100,000 maternities
    • Pre-conceptional care and cardiac disease
      • Expert assessment, advice and counselling
      • Fully closed structural defects = low risk: otherwise high risk
      • Risk of pregnancy, childbirth, puerperium explained.
      • Echocardiography in some disorders (e.g. cardiomyopathy)
      • Genetic counselling if necessary (risk of inheritance, e.g. Marfans)
      • Long term affects of cardiac disease (Life expectancy)
      • MRI scan, in some disorders
    • Pregnancy Care
      • Joint obstetric cardiac clinics and multidisciplinary care plans
      • Communication shared with woman and all clinicians involved in her care, all writing in the womans hand held notes.
      • Early involvement of senior obstetricians and cardiologists wherever cardiac disease is suspected (MBBRACE, 2016)
      • Early booking is essential - accurate family and personal history
      • Pregnancy increases risk of arrhythmia, heart murmurs, stroke, heart failure, PE, pre-eclampsia, endocarditis, pulmonary hypertension, aortic dissection, etc.
      • Is it safe to continue the pregnancy? Advice and counselling
      • Early and regular fetal screening
      • Medication review- may need diuretics, anticoagulants, beta-blockers
      • Some conditions may require pacemakers
      • Follow up defaulters
      • Obs at each AN appointment
      • Clear plan of management for labour and birth
      • Weight, diet management. Avoid anaemia
      • Close vigilance for symptoms of deteriorating condition e.g. breathlessness
      • Admission for bed rest, O2 therapy, O2 sats, may be required.
      • Access to MRI and echocardiogram
      • Preparation for possible pre-term delivery, IOL, or planned C/S
      • Plan for PN support at home/care of baby in the event of maternal death
    • Labour Care
      • Raised resp. rate, chest pains, persistent tachycardia and orthopnoea (shortness of breath when supine) should always be fully investigated
      • All consultant led maternity units should have ready access to an ECG machine and someone who can interpret ECGs.. Echocardiography should be available 7 days a week (MBBRACE, 2016)
      • TED stockings
      • Avoid fluid overload
      • Anticoagulants as indicated - Warfarin for mums, Heparin for babies
      • Anaesthetic review
      • Prophylactic antibiotics as indicated
      • IV access
      • O2 sats if indicated
      • Pain relief to reduce stress and BP - epidural
      • 1 2 1 care
      • Very close monitoring - EFM and maternal obs
      • Avoid direct pushing, long second stage
      • Elective CS or assisted birth may be indicated
      • Oxytocin for third stage, NOT ergometrine/Syntocinon
    • Postnatal Care
      • Mother
        • May need to be managed on ITU
        • Medical review prior to discharge home
        • Early ambulation if indicated
        • Fluid balance monitoring
        • Careful observations- longer than usual
        • Plan of support at home to ensure sufficient rest, help with baby, minimize stress
        • Promote compliance with ongoing care
        • Plan of follow on care
        • Advise on reporting any deterioration of symptoms or new symptoms
        • Contraceptive advice
        • Remember: Most maternal deaths occur in the postnatal period
      • Baby
        • BF check before advocating this, as may be contraindicated e.g. some forms of cardiomyopathy or with certain maternal medications
        • NIPE by paediatric registrar or consultant, not midwife or student
        • May require NICE/SCBU admission for treatment or monitoring
        • May require referral to specialist unit or long term follow-up
        • Ensure baby being suitably  cared for if mother is unwell
  • Cardiomyopathy
    • 1:5000
    • Characterised by ventricular dysfunction, cardiac failure
    • Severe types
    • May be genetic
    • May occur for first time in late pregnancy
    • Symptoms difficult to to differentiate from normal changes in pregnancy
    • Requires multi-drug therapy and pacemaker/ defibrillator
    • Risk of sudden death, hence TOP may be advised
  • Ischaemic heart disease
    • 1:10,000 - 1:30,000
    • Due to inadequate blood flow to coronary arteries
    • May lead to Angina and Myocardial Infarction (MI)
    • Typical symptoms include...
      • Chest pain
      • Sweating
      • Feeling of doom
      • Breathlessness
      • Dizziness
      • Vomiting
      • Can be asymptomatic
    • Risk Factors
      • Over 35years
      • smokers
      • obese
      • diabetes
      • cocaine use
      • Family history
      • Black or Asian ethnicity
    • MI = 37-50% RISK OF DEATH

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