biology topic two

  • Created by: jessicate
  • Created on: 01-08-18 12:19
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  • biology topic two
    • cystic fibrosis
      • is a result from one of a number of possible gene mutations
      • understand how the expression of a gene mutation in people with cystic fibrosis impairs the functioning of the gaseous exchange, digestive and reproductive systems
    • properties of transport materials across cell membranes and gas exchange surfaces
      • know the properties of gas exchange surfaces in living organisms
      • understand how the rate of diffusion is dependent on these properties and can be calculated using Fick's law of diffusion
      • understand how the structure of the mammalian lung is designed for rapid gas exchange
      • know the structure and properties of cell membranes
      • understand how models are used to interpret data for scientific explanations
      • movement in cells: osmosis, passive transport, active transport, endocytosis and exocytosis
      • understand the involvement of carrier and channel proteins in membrane transport
    • DNA structure and replication
      • know the structure of  mononucleotides and structures of DNA and RNA
      • double helix: complementary base pairing and hydrogen bonding between two complementary strands are involved in the formation.
      • protein synthesis process: RNA polymerase, translation, messanger RNA, transfer RNA, robosomes and the role of start and stop codons
      • understand the roles of: DNA template strand in transcription, codons on messenger RNA and anti-codons on transfer RNA
      • understand the nature of the genetic code
      • a gene is a sequence of bases on a DNA molecule that codes for a sequence of amino acids in a polypeptide chain
      • understand the process of DNA replication, including the role of DNA polymerase
      • unsderstand how meselson and stahl's classic experiment provided new data that  supported the accepted theory of replication of DNA and refuted competing theories
      • understsnd how errors in DNA replication can give rise to mutations
    • proteins
      • know the basic structure of an amino acid
      • understand the significance of a proteins primary structure in determining its 3D structure and properties
      • understand the formation of polypeptides and proteins
      • protein synthesis
      • know the molecular structure of a globular protein and a fibrous protein and understand how their structures relate to their functions
      • understand the mechanism of action and the specificity of enzymes in terms of tehir 3D structure
      • enzymes are biological catalysts that reduce activation energy
      • there are inracelluar enzymes catalysing inside cells and extracellular enzymes produced by cells catalysing reactuions outside of cells
    • enzymes and monohybrid inheritance through the context of the genetic disease cystic fibrosis
      • understand the meaning of the terms: gene, allele, genotyoe, phenotyoe, reccesive, dominant, imcomplete dominance, homozygote and heterozygote
      • understand patterns of inheritance inlcuding the interpretation of genetic pedigree diagrams, in the context of monohybrid inheritance
    • social amd ethical issues surrounding genetic screening for genetic conditions
      • understand the uses of gentic screening, including the identification of carriers, pre-implantation genetic diagnosis and prenatal testing including amniocentesis and chorionic villus sampling
      • understand the implications of prenatal genetic screening
      • be able to identify and discuss the social and ethical issues related to genetic screening from a range of ethical veiwpoints
    • maths
      • areas of shapes
      • volumes
      • fractions and percentages
      • ratios
      • plotting data
      • interpreting graphs


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