Biology B - Topic 4 (Part 1)

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  • Created by: patiw2004
  • Created on: 21-06-21 18:13
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  • Biology B: Topic 4
    • The Heart
      • Tricuspid Valve separates the right atrium and ventricle
      • Semilunar Valve separates the ventricles from the pulmonary artery/vein
      • Bicuspid Valve separates the left atrium and ventricle
    • Circulation
      • Single Circulation
        • Two-chambered heart
        • deoxygenated blood is pumped from the heart to the gills
        • oxygen is given to body cells before returning to the heart
        • Blood becomes oxygenated in the gills
      • Double Circulation
        • Involves two circulatory systems: systematic and pulmonary
        • Systematic: oxygenated blood from heart to body cells, deoxygenated blood back to heart
        • Pulmonary: deoxygenated blood from heart to lungs,, carries back oxygenated blood to the heart
        • Four chamber heart: right atrium, right ventricle, left atrium, left ventricle (separated by valves to prevent backflow)
        • Mammals must maintain high body temperature and move without support of water
        • more oxygen and glucose is used up as it requires more energy
    • Roles of Blood
      • Erythrocytes
        • Contain Hb which binds to oxygen
        • small in size and have a biconcave shape
        • large SA:V to aid oxygen diffusion
        • lack nucleus
      • Leucocytes
        • white blood cells
        • involved in defence against infection
      • Plasma
        • carries water-soluble materials
        • carries digested food molecules, excretory products & hormones
        • maintains body temperature by transferring heat energy
        • buffer to pH change
        • contains platelets (involved in blood clotting)
      • Neutrophils and Monocytes
        • Engulf and digest pathogens by phagocytosis
      • Eosinophils
        • allergic responses & protection against viruses and parasitic worms
      • Lymphocytes
        • natural killer cells, include formation of antibodies
    • Blood Circulation
      • Arteries
        • Carry oxygenated blood from heart around body
      • Veins
        • Carry deoxygenated blood back toward the heart
      • Capillaries
        • Narrow vessels link arteries and veins
        • pass very close to cells
        • arterioles feed into networks of capillaries
        • walls allow rapid diffusion
      • Valves
        • Prevent backflow, one way blood flow to heart
        • needed as there is low pressure in veins
    • Transporting o2 and co2
      • Oxygen Dissociation Curve of Hb
        • Hb is ideally suited to pick up o2 at the lung and drop it off at the tissues
        • shows percentage saturation of Hb with o2 in relation to how much o2 is available in the environment
      • The Bohr Effect
        • Effect of co2 on the o2 dissociation curve of Hb
        • high co2 = reduced affinity, Hb binds with o2 less well
        • Hb needs higher levels of o2 to become saturated
        • low co2 = increased affinity, Hb binds with o2more easily
      • Oxygen Dissociation Curve of pH
        • pH decrease = graph shift right, drop in affinity
        • H+ makes solution acidic, near muscles and cells
      • Curve Shift to the LEFT: Low levels of co2, low temp. High pH, high affinity of Hb
      • Curve Shift to the RIGHT: High levels of co2, high temp. Low pH, low affinity of Hb
    • Blood Clotting Cascade
      • prothrombin   -> thrombin by thrombo-plastin
      • soluble fibrinogen-> fibrin by thrombin
    • Valves Opening and Closing
      • Semi-lunar Valve
        • Open: ventricles > aorta & pulmonary artery
        • Close: aorta & pulmonary artery > ventricles
      • Atrio-ventricular Valve
        • Open: atria > ventricles
        • Close: ventricles > atria
      • ECG Graph
        • A: AV Valves close, B: SL Valves open, C: SL Valves close, D: AV Valves open
    • Cardiac Cycle
      • Atrial Systole, Ventricular Systole, Diastole
    • Controlling the Heart
      • If there is no P-Wave, no contraction, no electrical impulse, no depolarising

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