Biological Therapies for Schizophrenia
Mindmap for the Biological Therapies for Schizophrenia including procedures, how they work and their evaluations as to their effectiveness and appropriateness.
- Created by: Catriona Stobie
- Created on: 05-01-14 16:51
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- Biological Therapies for Schizophrenia
- ECT
- Procedure
- Evaluation
- Effectiveness
- Tang found that ECT works well for those who don't respond to drug therapy.
- Tharyan & Adams conducted a review of 26 studies including 798 pps. They found that when compared to a placebo version of ECT more people improved in the real ECT condition. ECT was even more effective when combined with drug therapy.
- Up to 50% of patients relapse within the first 6 months so ECT is not a long term cure
- Appropriateness
- seen as highly unethical as it can be seen as a barbaric method
- ECT is no more dangerous than any other minor surgery performed under general anaesthetic
- Effectiveness
- Drug Therapy
- How They Work
- Typical drugs bind to the dopamine receptors and so block them so dopamine itself cannot bind.
- This helps to alleviate positive symptoms of schizophrenia
- Based on the dopamine hypothesis
- Atypical drugs work in a similar way to typical drugs but they also affect serotonin activity too in order to increase mood and help relieve other symptoms
- Typical drugs bind to the dopamine receptors and so block them so dopamine itself cannot bind.
- Evaluation
- Effectiveness
- Davis et al found a significant difference in terms of relapse rates between treatment and placebo groups. Treatment groups performed much better.
- Older atypical drugs are ineffective in treating negative symptoms of Sz. Clozapine however does help these symptoms.
- Drugs are not a cure and so when treatment stops the symptoms reappear
- Drugs do not work for 15% of patients
- Relatively economical and easy to administer
- Appropriateness
- Drugs can cause a variety of bad side effects and are not appropriate for some patients because of this
- Some people stop taking medication because of side effects, suggesting whether or not it is unethical to stop patients from having the right to refuse medication.
- Newer drugs that have less side effects, such as Clozapine, have an adverse effect on the immune system, meaning a lot of money needs to be spent in order to ensure patients remain healthy
- Adverse side effects sometimes lead to the revolving door effect. Patients stop taking medication and have to go back into hospital time and time again due to repeated relapse
- Some people stop taking medication because of side effects, suggesting whether or not it is unethical to stop patients from having the right to refuse medication.
- Drugs can cause a variety of bad side effects and are not appropriate for some patients because of this
- Effectiveness
- How They Work
- ECT
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