Biological Explanations for Schizophrenia
- Created by: Jwalker5
- Created on: 04-02-14 15:37
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- Biological Explanations
- Genetics
- Family Studies
- Gottesman
- 2 SZ parents - 46%. 1 SZ Parent - 13% Siblings w SZ - 9%
- Gottesman
- Twin Studies
- Joseph
- MZ - 40.4% DZ - 7.4%
- Joseph
- Adoption Studies
- Tienari et al
- 164 w mothers w. SZ -- 11 had SZ. 197 control wt. SZ - 4 had SZ
- Tienari et al
- Inherit genes from our parents
- 32 pairs of chromosomes from each. Leaving a predisposition to certain disorders
- SZ Spectrum Disorder sometimes included into diagnosis of SZ
- Psychological Explanations not included
- Family Studies
- Dopamine Hypothesis
- Dopamine is a neurontransmitter that guides attention
- High levels of dopamine linked to SZ
- Too many D2 receptors collect dopamine too much
- High levels of dopamine linked to SZ
- Anti-psychotics
- Dopamine Antagonist - reduces stimulation of dopamine and eliminates hallucinations etc.
- L-Dopa
- Low levels of dopamine are found in Parkinson's patients.
- They're given L-Dopa tp raise levels and found they develop SZ symptoms
- Low levels of dopamine are found in Parkinson's patients.
- Amphetamine
- Dopamine Agonist - stimulates dopamine cyaing synapse to flood. Large does cause hallucainations
- Haracz - found those who showed high dopamine before death had received anti-psychotics
- PET Scans - neuroimaging - failed to provide evidence that dopamine affects SZ
- Dopamine is a neurontransmitter that guides attention
- Genetics
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