Biological explanations
- Created by: ellalouise_
- Created on: 28-02-19 11:41
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- Biological Explanations
- Family Studies
- The closer they are related the more likely they are to get schitz through genetics
- Grottesman found if they have 2 schitz parents the concordance rates are 46% compared to 13% for one schitz parent
- Twin Studies
- Mz twins= 40.4% con rate.
- Dz twins= 7.4% con rate.
- Adoption Studies
- If a biological parent has it and so does the child it is to do with genetics
- Adopted parent has to and so does child it is to do with the environment
- Tienari et al (2000) did a study in Finland on 164 adopted children.
- If their biological mother had schitz 11 of them recieved a diagnosis
- If their biological mother didnt have schitz only 4 was diagnosed
- Dopamine Hypothesis
- Excess of dopamine can cause positive symptoms
- Revised Dopamine Hypothesis
- Deficit in prefrontal cortex can lead to negative symptoms
- Dopaminergic Activity
- Amphetamine increases dopamine which can cause development of schitz
- Drugs that decrease dopamine levels decrease the risk pf schitz
- Specific Brain Areas
- Deficits in nerve connections between hippocampus and pfc cause memory impairments
- The prefrontal cortex is impaired in schitz patients
- Matter
- Grey matter is reduced in temporal and frontal lobes in schitz
- White matter is reduced in the brain and spinal cord in schitz
- Family Studies
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