Biological explanations of obesity

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  • Created by: katiewho
  • Created on: 10-03-17 09:44
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  • Biological Approach for Obesity
    • Stats
      • Type 2 diabetes increased 10% since 1996
      • Obesity has increased since 1990s
    • Genetic Theories
      • Family Clusters
        • 1 obese parent = 40% risk
        • 2 obese parents = 80% risk
        • No obese parents = 7% risk
      • Twins
        • MZ raised apart = more similar in weight
        • 66% to 70% heritability
        • Genetics appear stronger in lighter twins
    • Metabolic Rate Theory
      • RMR is highly heritable
    • Appetite Regulation
      • Appetite control depends on agentic pre-disposition
      • 2 children identified with defect in their ob gene
        • Ob gene produces leptin
          • Leptin: inhibits hunger. Makes us feel full.
          • Released from fat cells sends signals to hypothalamus
        • Injected with leptin
          • Lost 1-2kg per month
          • RWA
    • Neural Model
      • Hypothalamus is associated with obesity
        • Abnormality in the VMH
        • Post mortem showed that some obese females had a damaged VMH
          • Can't claim cause and effect
        • Regulates the metabolism
        • NPY = starts eating
          • VMH = stops eating
      • Evaluation of Neural Model
        • RWA - leptin injections
          • Only works in a few people - is leptin really important?
    • Evaluation
      • Doesn't explain why obesity is on the increase today - our gene pool has remained constant
      • Unclear how genes are involved to obesity and to what extent
      • Doesn't explain why geographical relocation to obesogenic environment often causes individuals to gain weight
        • Evolutionary does

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