Bacterial RNA Polymerase

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  • Created by: Ellie0o0o
  • Created on: 23-04-15 11:52
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  • Bacterial RNA polymerase
    • Multi-subunit
      • Core
        • Alpha I
          • Enzyme assembly
        • Alpha II
          • Enzyme assembly
        • Beta
          • Catalytic site
        • Beta-i
          • Catalytic site
        • Omega
          • Enzyme assembly
      • Sigma
        • Promoter recognition and binding
        • Aided by sigma factors
          • Elongated shape
          • Sit on the outer face of the polymerase
          • "house-keeping" or "alternative"
            • Sigma 70
              • Primary house-keeping
            • Sigma 5 - Stress
              • Sigma 32 - Heat shock
                • Sigma E - Extreme heat shock
                  • Sigma 54 - Nitrogen starvation
                    • Sigma 28 - Flagella synthesis
    • Enzyme
    • Interaction channel
      • Holds 16bp
      • Lined with +ve charges
    • Target of antibiotics
      • Rafampicin targets beta subunit

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