Principles of Immunology, lecture 3, antibodies
- Created by: Jessica Robinson
- Created on: 20-03-13 22:02
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- Antibodies
- IgG
- Secondary immune response
- Opsonisation
- Complement activation
- Transplacental passage
- Blood: 8-16g/L
- Monomer
- IgM
- Primary immune response
- Complement activation
- Agglutination
- Only found in vascular system
- Blood: 0.5-2g/L
- Molecular Weight: 900 KDaltons
- Pentamer
- Serum concentration: 1.5g/L
- IgA
- Secretions
- Trimer
- High levels in first breast milk
- Transplacental passage
- Dimer
- Secretions
- Trimer
- Secretions
- Tetramer
- Molecular Weight: 150-600 KDaltons
- Serum concentration: 1.5-4g/L
- Secretions
- IgM
- Molecular Weight: 150 KDaltons
- Serum: 0.5-9g/L
- IgM
- Primary immune response
- Agglutination
- Only found in vascular system
- Blood: 0.5-2g/L
- Molecular Weight: 900 KDaltons
- Pentamer
- Serum concentration: 1.5g/L
- IgA
- High levels in first breast milk
- Dimer
- Tetramer
- Molecular Weight: 150-600 KDaltons
- Serum concentration: 1.5-4g/L
- High levels in first breast milk
- IgE
- Protection against parasitic worm infestation
- Serum: 0.0003g/L
- Allergies
- Monomer
- Molecular Weigh: 190 KDaltons
- no useful antibodies in blood
- serum: 0.015-0.04g/L
- IgD
- no useful antibodies in blood
- serum: 0.015-0.04g/L
- membrane bound
- same variable regions
- Role a mystery
- no useful antibodies in blood
- IgG
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