6.3 Antibiotics
- Created by: Eva
- Created on: 10-01-13 19:22
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- Antibiotics
- Disrupt the biochemistry of bacterial cells leading to their destruction
- Selective toxicity: interferes with the metabolism/ function of the pathogen but minimal damage to host
- Bacteriostatic
- Inhibits the growth or reproduction of pathogens.
- Used for everyday infections
- Bacteriocidal
- Kills bacteria - almost 100%.
- For severe infections.
- Broad spectrum destroy a range of pathogens
- Narrow spectrum destroy one or two specific pathogens
- How to investigate effectiveness
- Seed agar plate with known bacterial culture
- Types
- Antimetabolites
- Cell wall agents
- Cell membrane agents
- Protein synthesis inhibitors
- DNA gyrase inhibitors
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