6.3 Antibiotics

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  • Created by: Eva
  • Created on: 10-01-13 19:22
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  • Antibiotics
    • Disrupt the biochemistry of bacterial cells leading to their destruction
    • Selective toxicity: interferes with the metabolism/ function of the pathogen but minimal damage to host
    • Bacteriostatic
      • Inhibits the growth or reproduction of pathogens.
      • Used for everyday infections
    • Bacteriocidal
      • Kills bacteria  - almost 100%.
      • For severe infections.
    • Broad spectrum destroy a range of pathogens
    • Narrow spectrum destroy one or two specific pathogens
    • How to investigate effectiveness
      • Seed agar plate with known bacterial culture
    • Types
      • Antimetabolites
      • Cell wall agents
      • Cell membrane agents
      • Protein synthesis inhibitors
      • DNA gyrase inhibitors


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