6.10 absorption of products of digestion

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  • 6.10 Absorption of products of digestion
    • The structure of the ileum
      • Adapt. to function of absorption
      • Wall folded & finger-like projections (villus)
        • ^SA -> accelerate rate of absorption
        • Villus situated interface BTWN lumen of intest + blood/ othr tiss inside body
          • Part specialised exchange surface adap for absorp
            • ^SA for diffusion
            • Thin walled, reducing diffusion path
            • cont. muscle so able to move -> help maintain diff gradient bc movement mix contents ileum
            • Well sup w/ blood vessels so blood carry away abs mol - maint diff gradient
            • Epithelial cells lining villus possess microvillus - further ^ SA
      • Thin walls, lined w/ epith cells on opp side which rich with network blood capil.
    • Absorption of AA and monosaccharides
      • digest prot produce AA
      • digest monosacc -> glucose, fructose & galactose
      • Diffusion & co-transport
    • Absorption Triglycerides
      • Once formed during digest. Monogly & FA remain associated w/ bile salts that initially emulsified lipid droplets
      • Struc formed called micelles - tiny - 4-7nm.
        • Thro move mat w/n lumen, micelles in contact w/ epithelial cells, lining villi of lumen
        • Micelles breakdown, releasing monoglyc & FA.
          • As non-polar mol - easy diffuse across CSM into epithelial cell
            • Once indise epith, monoglyc + FA transport to endoplasmic reticulum where recombined to form triglycerides.
              • Starting in ER & ending at Golgi A, triglyc associate w/ cholesterol & lipoproteins to form struc: chylomicrons - adapted to transport lipids
                • Chlyomicrons move out of epithelial cells by exocytosis.
                  • Enter lymphatic capillaries called lacteals in centre of each villus

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